Search | Result
| ID | 1277 |
|---|---|
| Class | Mammalia |
| Species | Homo sapiens |
| Tissue | Blood |
| Sample | Blood |
| Disease type | NA |
| Cell type | T cells |
| Cell type (subtype) | Cytotoxic T cells |
| Cell marker | PDCD1, LAG3, TIGIT, HAVCR2 |
| Frequency | |
| PubMed ID | 33409501 |
| Journal | Nat Cancer |
| SCI IF | NA |
| Evidence | We next examined whether these populations displayed characteristics of T cell exhaustion. Of four key markers of exhaustion (PDCD1, HAVCR2, LAG3, TIGIT), we found only LAG3 and TIGIT are expressed at detectable levels, and are relatively specific to the cytotoxic subsets |
| Title | Single-cell RNA sequencing reveals compromised immune microenvironment in precursor stages of multiple myeloma. |
| Authors | Oksana Zavidij et al. |
| Date | 2020 |
| Data available | GSE124310 |
