Evidence |
Manuscrip Unsupervised clustering identified several PBMC subsets based on canonical marker genes(SupplementaryFig.1A). These included CD14+ monocytes, CD16+ monocytes, classical dendritic cells(cDCs), plasmacytoid pre-DCs(pDCs), NK cells, B-cells, and three T-cell populations, which all expressed CD3D, CD3E and TRAC and were further classified into conventional CD4+ T-cells(CD4, MAL), conventional CD8+ T-cells(CD8A, CD8B) and MAIT cells(NCR3, SLC4A10, RORC, DPP4, ZBTB16)[5](Fig.1A and SupplementaryFig.1A-B). |