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ID 6991
Class Mammalia
Species Mouse
Tissue Kidney
Sample Tissue
Disease type Kidney injury and fibrosis
Cell type T cells
Cell type (subtype) T helper 1 effector cells
Cell marker Ifng, Nkg7, Ccl5, Ccl4
Frequency
PubMed ID 32051345
Journal JCI Insight
SCI IF 6.205
Evidence However, based on canonical markers, we could identify the following cell clusters clusters 1 and 2, Th1/effector cells (Ifng, Nkg7, Ccl4, and Ccl5); cluster 3, naive T cell Ccr7, Lef1, Satb1, Sell, and others); cluster 4, Th17 cells (Il17a, Tmem176a, and Tmem176b); and cluster 5, Tregs (Ikzf2, Klrg1, Foxp3, IL2ra, and others) (Figure 3B).
Title Immune cell landscaping reveals a protective role for regulatory T cells during kidney injury and fibrosis
Authors Fernanda do Valle Duraes et al.
Date 2020.2
Data available E-MTAB-7957, E-MTAB-7961, and E-MTAB-8002