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ID 1221
Class Mammalia
Species Homo sapiens
Tissue Blood
Sample Blood
Disease type Hodgkin lymphoma
Cell type T cells
Cell type (subtype) Cytotoxic T cells
Cell marker CD3, CD4, CD8, GZMA, GNLY, GZMK
Frequency
PubMed ID 31857391
Journal Cancer Discov
SCI IF 29.497
Evidence CD8, CD3, CD4 (T85 cells), NCAM1 (NK cells), GNLY, GZMA, GZMK (cytotoxic T cells, NK cells), 86 IL2RA, FOXP3, CTLA4, LAG3, TNFRSF18, IKZF2, IKZF4, LGMN (Tregs), IFNG, 87 TBX21 (Th1 cells) GATA-3, CRTH2, IL4, IL13 (Th2 cells), CD161, CCR4 (Th17 88 cells), PDCD1, CXCR5, BCL6 (TFH cells), CCR7, IL7R, LEF1 (Naive T cells), CD25, CD89, CD69 (activated T cells)
Title Single-Cell Transcriptome Analysis Reveals Disease-Defining T-cell Subsets in the Tumor Microenvironment of Classic Hodgkin Lymphoma
Authors Tomohiro Aoki et al.
Date 2019.12
Data available NA