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ID 1202
Class Mammalia
Species Homo sapiens
Tissue Blood
Sample Tissue
Disease type MGUS/MM
Cell type T cells
Cell type (subtype) Exhaustion
Cell marker PRDM1
Frequency
PubMed ID 31013254
Journal JCI Insight
SCI IF 6.205
Evidence the T3 cluster in MM revealed enrichment of PRDM1 (as a marker of exhaustion), Fos, and CCL4 (as a marker of activation) and downregulation of granulysin and lysozyme (as a marker of dysfunction)
Title Early alterations in stem-like/marrow- resident T cells and innate and myeloid cells in preneoplastic gammopathy
Authors Jithendra Kini Bailur et al.
Date 2019.4
Data available NA