Search | Result
| ID | 768 |
|---|---|
| Class | Mammalia |
| Species | Homo sapiens |
| Tissue | Blood |
| Sample | Cell line |
| Disease type | END(endoderm)-Diff |
| Cell type | Stem cell |
| Cell type (subtype) | Cluster3 |
| Cell marker | NODAL, EOMES, GATA6, HHEX |
| Frequency | |
| PubMed ID | 30995470 |
| Journal | Cell Rep |
| SCI IF | 9.423 |
| Evidence | Cluster 3 expresses the highest levels of the mesendoderm markers MIXL1, EOMES, and T, while expression of END markers is either low (e.g., FOXA2, CXCR4, GATA4) or high (e.g., GATA6, NODAL, HHEX; Figure 2C). |
| Title | Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development |
| Authors | Ryan M.J. Genga et al. |
| Date | 2019.4 |
| Data available | GSE127202 |
