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ID 2177
Class Mammalia
Species Homo sapiens
Tissue Epididymis
Sample Tissue
Disease type Testicular cancer
Cell type Sperm
Cell type (subtype) Sperm
Cell marker CFAP43, FOXJ1
Frequency
PubMed ID 32855272
Journal Life Sci Alliance
SCI IF 2.623
Evidence One classical marker of principal cells in the mammalian epididymis is the water channel aquaporin 9 (AQP9), we present evidence that cluster 1 cells may encompass apical and narrow cells, rather than principal cells. The next most abundant cluster of cells (cluster 2) is primarily contributed by donors AXH012 and AXH014 and inspection of the DEG list suggests these may arise from ED cells contaminating the caput tissues. The diagnostic marker for the ED is villin (VIL1), which is apparently abundant in the ED epithelium but not seen in the caput epithelium in tissue sections
Title An atlas of human proximal epididymis reveals cell-specific functions and distinct roles for CFTR
Authors Shih-Hsing Leir et al.
Date 2020.8
Data available NA