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ID 1027
Class Mammalia
Species Homo sapiens
Tissue Blood
Sample Blood
Disease type Inherited ISG15 Deficiency Leads to Necrotizing Skin Lesions
Cell type Dendritic cells
Cell type (subtype) Dendritic cells
Cell marker CD11c
Frequency
PubMed ID 32402279
Journal Cell Rep
SCI IF 9.423
Evidence monocyte subsets (CD14+CD16_, CD14+CD16+, and CD14_CD16+) and myeloid dendritic cells (Lin_CD11c+, including CD1c+_DC2s] and CD141+_DC1s]) had significantly higher levels of SIGLEC1 expression (Figures 3C_nd_and3D)3D) than the corresponding control cellsFigure4A, B
Title Systemic Type I IFN Inflammation in Human ISG15 Deficiency Leads to Necrotizing Skin Lesions
Authors Marta Martin-Fernandez et al.
Date 2020.5
Data available NA